Sl. No | Name of Disease | Age at first dose | Booster dose | Subsequent dose |
1 | Foot and Mouth Disease (FMD) |
4 months and above | 1 month after first dose | Six monthly |
2 | Haemorrhagic Septicaemia (HS) |
6 months and above | - | Annually in endemic areas. |
3 | Black Quarter (BQ) | 6 months and above | - | Annually in endemic areas. |
4 | Brucellosis | 4-8 months of age (Only female calves) |
- | Once in a lifetime |
5 | Theileriosis | 3 months of age and above | - | Once in a lifetime. Only required for crossbred and exotic cattle. |
6 | Anthrax | 4 months and above | - | Annually in endemic areas. |
7 | IBR | 3 months and above | 1 month after first dose | Six monthly (vaccine presently not produced in India) |
8 |
Rabies (Post bite therapy only) |
Immediately after suspected bite. | 4th day | 7,14,28 and 90 (optional) days after first dose. |
Source : NDDB Handbook of Good Dairy Husbandry Practices
Infection |
Manufacturer |
Ingredients/adjuvant |
Dose |
Primary |
Booster |
Revaccination |
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FMD |
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Bovilis®Clovax |
Intervet India |
Binary ethyleneimine (BEI) inactivated FMD mineral oil emulsion vaccine containing a mixture of virus serotypes O, A and Asia-1 |
2ml, i/m (Vial: 100 ml) |
3 months onwards |
I After 4-6 weeks of primary vaccination II After 24 weeks of first booster |
Every 44-48 weeks after 2nd booster vaccination |
|||
Raksha |
Indian Immunologicals |
Inactivated tissue culture FMD virus strains O, A and Asia-1 adsorbed on Al (OH)3 gel and saponin as an adjuvant |
3 ml in the mid-neck region, s/c (Vial: 30 ml) |
4 months |
2-4 weeks after primary vaccination |
Every 6 months after booster and every 4 months in endemic areas |
|||
Raksha Ovac |
-do- |
Inactivated tissue culture FMD virus strains O, A, and Asia-1 adjuvanted with mineral oil |
2 ml in the mid-neck region, deep i/m |
4 months |
9 months after primary vaccination |
Annually |
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Haemorrhagic Septicemia (Galghotu/Ghurrka) |
|||||||||
Raksha HS |
Indian Immunologicals |
Formaldehyde inactivated culture of Pasteurella multocida adsorbed on aluminium hydroxide gel |
2 ml, mid-neck region, s/c (Vial:100 ml) |
6 months and above |
Annually and in adverse climatic conditions like unseasonal rains and cyclones, etc. |
||||
Compound Vaccines of FMD/HS/BQ |
|||||||||
Raksha biovac (FMD+HS) |
Indian Immunologicals |
FMD inactivated antigens against O, A, and Asia-1 strains and formaldehyde inactivated Pasteurella multocida culture mixed together in light mineral oil emulsion |
3 ml, midneck, deep i/m (Vial: 30 ml) |
4 months |
9 months |
Annually |
|||
Raksha triovac (FMD+HS+BQ) |
-do- |
FMD inactivated antigens against O, A, Asia-1 and formaldehyde inactivated Pasteurella multocida culture, inactivated Clostridium chauvoei culture mixed together in light mineral oil emulsion |
3 ml, mid-neck, deep i/m (Vial: 30 ml) |
4 months |
9 months |
Annually |
|||
Raksha HS+BQ |
-do- |
Formaldehyde inactivated cultures of Pasteurella multocida and Clostridium chauvoei adsorbed on aluminium hydroxide gel |
3 ml, mid-neck region, s/c (Vial: 90 ml) |
6 months and above |
Annually and in adverse climatic conditions like unseasonal rains and cyclones, etc. |
||||
Brucellosis |
|||||||||
Bruvax |
Indian Immunologicals |
Live Brucella abortus strain 19 freeze dried bacteria, each dose ≥ 40x109 organisms |
2 ml., s/c (Vial: 5 dose freeze dried vaccine with 10 ml sterile diluent) |
4-8 months old serologically negative female calves |
|||||
Note:Only serologically negative female calves should be vaccinated with live B. abortus strain 19 while bulls and pregnant animals should not be vaccinated |
|||||||||
Depending upon prevalence in a given area, vaccination against following diseases may also be taken up Anthrax |
|||||||||
Raksha-Anthrax (Prophylactic only) |
Indian Immunologicals |
Suspension of live spores of attenuated non-capsulated strain of B. anthracis in 50% glycerinated saline, each dose ≥ 1x108 viable spores |
1 ml, i/m or s/c (Vial: 50 ml) |
one month before grazing season or prior to the time the disease usually occurs |
|||||
Note: Protect animals from overexertion 3 days following vaccination. Do not vaccinate the animal 60 days before slaughter |
|||||||||
Sterne Vaccine |
Institute of Veterinary Preventive Medicine, Tamil Nadu |
**Live spores of highly antigenic nonencapsulated avirulent Sterne strain (34 F2) of B. anthracis in glycerine saline |
1 ml, s/c |
Approx. 4 weeks prior to the time the disease usually appears |
Revaccinate after 2-3 weeks in heavily contaminated areas |
annual vaccination in endemic areas |
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Note: Use boiled milk from lactating animals up to 1 month after vaccination, do not vaccinate within 42 days before slaughter, do not give antibiotics to animals being vaccinated; burn, autoclave or chemically disinfect container and all unused contents; adrenalin should be administered immediately if anaphylactoid reaction occurs, immunity 6m-1year |
|||||||||
Rabies |
|||||||||
Raksharab, Prophylactic |
Indian Immunologicals |
***Tissue culture rabies virus, CVS strain adjuvanted with Al(OH)3 adjuvant, antigen potency >2.5 IU/ml |
1 ml by s/c or i/m route (Vial: 1 ml, 5 ml, 10 ml) |
3 m and above |
In case primary vaccination is given below 3 months of age, a booster dose should be given at 3 months age |
3 years, annual vaccination recommended in endemic areas |
|||
Post-exposure therapy (PET) |
I-Day Zero of dog bite or within 24 hrs, II-Day 3, III-Day 7, IV-Day 14, V- Day 28 and VI-Day 90 |
||||||||
Note: Vaccinate only healthy animals; malnutrition, helminth infestation, administration of immunosuppressive agents like corticosteroids, radiation therapy, etc. will suppress immune response to vaccine; generally no adverse reactions are noticed, occasionally a transient, palpable nodule may occur at the site of injection; in rare cases hypersensitivity may occur, immediate treatment with antihistaminics is advocated. |
Source : Buffalopedia
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